Lizzo appears to be taking the long-running animated series South Park in stride after the show mocked her in a recent episode.
The show aired a special on Paramount+ on Friday called “The End of Obesity,” featuring the singer as an alternative to the weight-loss drug Ozempic and harnessing the power of “not giving a damn.”
“FDA-approved Lizzo helps you feel good about your weight, and it’s priced 90% less than Ozempic,” the voiceover explains. “Case studies show that 70% of patients who take Lizzo stop worrying about their weight. Lizzo helps you eat all the things you love, while minimizing exercise.”
“I’ve lowered my standards and my expectations,” one character explains. “I don’t care!”
Lizzo was mocked on “South Park” as someone who takes the weight-loss drug Ozempic instead of taking it. (Joseph Okpako/WireImage/Getty Images)
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The ad adds, “Some patients report that listening to Lizzo makes them constipated…Serious side effects can include pancreatitis, hypothermia and literally pooping out of your ears.”
Lizzo is Instagram and TikTok They will react live to the scene on Saturday.
“My worst fears have come true,” Lizzo told fans, “They mentioned me in an episode of South Park. So scary. I’d do a blind duet right now.”
After the video, she commented, “It’s crazy. I really feel like I’m such a bitch. I really am such a bitch. I showed the world that I love myself and I don’t care. These guys in Colorado know who I am and they put me in a cartoon that’s been running for 25 years.”
She continued, “I’m such a bitch and I can teach you how to not care and I’m going to teach you how to not care.”

Responding to the South Park gag, Lizzo said she was “really that bitch.”
Fox News Digital has reached out to a spokesperson for Lizzo and representatives for “South Park” creators Matt Stone and Trey Parker for comment.
In recent years, “South Park” has been in the news for its attacks on sensitive topics such as diversity and transgender politics. In 2023, several clips from the show went viral mocking Disney for pushing diversity politics with its remakes and reboots.
Famous South Park clip mocks school’s transgender bathroom policy goes viral
The character Eric Cartman told his psychiatrist that he had a nightmare in which the students at his school were replaced with a more diverse group, saying, “I felt like screaming. I was like, ‘Why are they replacing all the characters with diverse people?’ And Kenny was like, ‘It’s not our fault, it’s Kathleen Kennedy’s fault,’ and Kathleen Kennedy was like, ‘Damn, make it more boring!'”

A 2023 episode of “South Park” poked fun at the trend of race-swapping famous characters in media. (South Park Studios YouTube Channel)
Cartman later recalls that in his dream, “Disney’s stock price kept going down and down and Bob Iger said, ‘No! No! What’s happening to my stock?'”
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Fox News’ Alexander Hall contributed to this report.
