Seattle had its three-game winning streak snapped by Detroit last week in a tight road game between the top teams in the NFC.
The Seahawks continued to perform well offensively, gaining 516 total yards. However, the defense struggled due to many inactive players, allowing 42 points on six touchdowns to five different players.
Meanwhile, the underdog Giants go on the road without one of their top producers on the offensive line, and another is questionable.
Here's a preview with betting odds, predictions and picks for Sunday's Giants vs. Seahawks game (4:25 p.m. CBS ET).
Giants vs. Seahawks odds
| team | spread | money line | over/under |
|---|---|---|---|
| giants | +6.5 (+100) | +250 | o42.5 (-110) |
| seahawks | -6.5 (-120) | -310 | u42.5 (-110) |
Giants vs. Seahawks predictions
The Giants also have their work cut out for them, dealing with crossing three time zones for this game, as Seattle's Lumen Field is one of the toughest venues and environments for a road team to win.
They also face a team with a top-tier rushing offense, according to Pro Football Focus. It's a bad matchup for the Giants, who rank 20th in run defense grade and have the ninth-most yards per rushing attempt in the NFL.
The G-Men's saving grace is their red zone defense, which has allowed opponents just 25% of touchdowns (second in the NFL) over the past three weeks on the road.
But Seattle was especially surgical in its red zone scoring at home, landing the punch 67% of the time (7th in the NFL). Last week against Detroit, the Seahawks scored inside the red zone (INT) on three of their four trips and also scored a touchdown on a Kenneth Walker run just outside the Lions' 20.
Making matters even worse for the Giants, the Seahawks are expected to return several key defensive players who were absent from last week's loss.
LB Jerome Baker, DL Leonard Williams, OLBs Boi Mafe and Uchenna Nwosu, and first-round pick DT Byron Murphy II all participated in Seattle's Monday Night Football game against Detroit. I was absent.
Baker, Williams and Nwosu have a good chance to return this week, giving Seattle a better chance to tighten up the Giants' run game, which was exposed in Week 4 against Dallas.
Devin Singletary gained just 24 yards on 14 carries (1.7 yards average).
Gaining meaningful yards on the ground and through the air may be difficult for the Giants.
The Seahawks lead in QB pressures, meaning Daniel Jones could continue to run away throughout the game.
Historically, Jones has struggled to throw under pressure, currently boasting the 24th-best quarterback rating and 25th-best completion percentage in the league, which is down to rookie wide receiver Malik through the first four games. It was made even better by the great play of Nabers.
However, Nabers (in concussion protocol) was ruled out of Sunday's game, a huge blow to an offense that was already struggling.
Singletary, who has a groin issue, is questionable to play.
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Giants vs. Seahawks nominations
Without Neighbors, it could be Singletary against a Seahawks defense that is getting back into shape, and the Giants are likely to have trouble moving the ball on offense.
This could be a huge blow to the home team.
Pick: Seahawks -6.5 (-120, bet 365)
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Andrew Norton has handicapped the NBA, WNBA, NFL, College Basketball, Football, UFC, and Golf. During the 2022-23 NBA season, he delivered an outstanding ROI of 14.1%, cashed in 60% of his NBA spread picks, and led Tallysight in SportsIQ metrics.





