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Our global anti-AIDS program has saved millions of lives — improve it, don't kill it

As one of the most influential and successful actions in the global battle against AIDS, Pepfer, short for the President's emergency plan for AIDS relief, has long enjoyed a rare air of bipartisan support in Washington. Credited Programs Saves over 26 million lives It was the best of Republican President George W. Bush since its launch in 2003, and sailed through a series of re-approval forms in both Republican and Democrat majority in Congress.

But now, Pepfer faces an existential threat after finding himself on the cross of partisan politics. Some lawmakers were surprised 21Abortion Report It is executed via a Pepfer-funded clinic in MozambiqueIt appears they are ready to close the program, which expires on March 25th, with one-year reapproval expired.

If Congress is unable to update or modify the program in the coming weeks, the prevention and treatment services that have been the basis for global advancements against HIV and AIDS will be severely disrupted. Approximately 20 million people living with HIV will lose access to the drugs they rely on to stay healthy. According to an analysis by the United Nations AIDS organization, UNAIDS, the long-term loss of Pepfer's funds is 10x increase HIV-related deaths worldwide took about 6.3 million people to live by the end of the decade.

But there's no need to end like this for Pepfar. Congress has the opportunity to do two important things at once. It can save and improve Pepfar, recognize its important role in the health of millions of people living with HIV, and ensure it becomes more efficient with the equipment needed to continue to succeed.

Several colleagues and I have outlined reforms that we believe can achieve both of these goals by leveraging decades of experience in the prevention and treatment of HIV. These suggestions we explain Lancet HIV And Policy Briefs by Duke Global Health Instituteproviding a roadmap to Congress and implementing strategies to better take on the changing landscape of HIV and AIDS worldwide, while maintaining the amazing legacy of Pepfer.

Our recommendations flow from the perception that the dynamics of the HIV pandemic have changed significantly since the formation of the dynamics of the HIV pandemic were formed in 2003. A record 5 million new cases of HIV According to UNAIDS, it was reported. Breakthroughs in HIV treatment and prevention strategies have done much to reduce the number of new cases, but remained surprisingly high in both wealthy and poor countries, and in fact have risen in places such as Peru, Brazil, the Philippines, Russia and parts of the United States. First time in 2023 More than half of 1.3 million new cases of HIV It occurred outside sub-Saharan Africa. This has long been the focus of Pepfer's heaviest investment.

These statistics speak of Pepfer's success, but also about the need to broaden its scope. Expanding the presence of Pepfer in Latin America, Eastern Europe, and Central and Southeast Asia will help regain traction in reducing new HIV cases, while also expanding the soft influence of US health diplomacy to regions of strategic importance to the country's foreign policy objectives.

However, to achieve this, Pepfar requires a more lean and less bureaucratic approach that ensures that resources reach their partners more directly and efficiently. It proposes organizational and funding changes that will reduce program costs by 20% within five years. These include integrating PEPFAR operations within the State Department, reducing redundancy in program implementation and evaluation, and introducing clearer paths to program management into local leadership.

We also invite PEPFAR to focus on the most cost-effective interventions, such as newly developed long-acting antiretroviral therapy, and to target groups at the highest risk of infection and infection.

These reforms should resonate with political leadership on both sides of the aisle. But they cannot be implemented overnight, nor can they pause in a program that is essential to the daily needs of millions of people living with HIV. The only way to save and improve Pepfar is for Congress to agree to a new five-year reaffirmation, giving the program the space needed to considerately readjust its operations and strategies.

Over the past few weeks, we have seen what a world without Pepfer looks like. An order suspending almost all foreign aid after the US State Department's January 24th order, HIV clinics in many countries are forced to closecauses confusion and confusion among healthcare workers and those who live with HIV.

For many of us, these scenes resulted in a disastrous response from the early days of the epidemic when we had to tell people there was little effective way to prevent death and suffering from AIDS and other HIV-related illnesses, and there was nothing we could do for them.

Pepfer was an important part of putting its time in the past, allowing scientific and clinical breakthroughs to give people living in HIV the opportunity to lead a long and healthy life. It would be a disgrace to turn your back on them now when the only thing we need to help them is the courage to act.

Chris Beyrer, MD, is Director of Duke Global Health Institute and Director of Duke University's Gary Hock Distinguished Medicine and Global Health. He is a former president of the International AIDS Association and serves on Pepfer's Scientific Advisory Committee. 

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