New Research Links Tests to Processed Food Consumption
Recent studies indicate that blood and urine tests can effectively gauge the intake of ultra-highly processed foods (UPFS) among individuals.
Utilizing machine learning, researchers from the National Institutes of Health (NIH) have discovered numerous metabolites—molecules generated during metabolism—that are associated with the consumption of processed foods.
As noted by a researcher from the Maryland National Cancer Institute, this team has successfully created a “biomarker score.” This score estimates UPFS consumption based on metabolites found in blood and urine samples.
The study involved analyzing baseline data from 718 elderly participants who provided urine and blood samples, alongside dietary reports over a year. Following this, small clinical trials were conducted with 20 adults, who spent two weeks consuming meals high in UPFS and another two weeks on meals devoid of such foods.
One of the researchers mentioned, “Our study established that numerous serum and urine metabolites are linked to the percentage of energy derived from ultra-highly processed food intake.” The findings were later published in the Journal Plos Medicine.
Traditionally, studies examining the health risks related to ultra-processed foods often depend on self-reported dietary questionnaires, which can introduce potential inaccuracies, according to the NIH.
By implementing objective biomarkers, these new blood and urine tests could minimize these errors, an area that’s capturing researchers’ interest. “It was indeed surprising to discover the involvement of UPF-correlated metabolites in diverse biological pathways, showcasing the complex interplay between diet and metabolome,” one of them remarked.
The NIH defines super-processed foods as “ready-to-eat or quickly manufactured products, typically high in calories yet low in essential nutrients.” Heavy intake of these foods has been linked to chronic illnesses, obesity, and various cancer types.
Future Implications
While the results are promising, the researchers emphasized that these new methods require further validation before they can be widely implemented. As current studies predominantly focus on older adults, more research is essential across different age demographics and dietary patterns.
“The metabolite scores need to be evaluated and refined for various populations with differing diets and levels of UPF intake,” the researcher acknowledged.
There’s hope that this method could aid future investigations into the relationship between processed food consumption and chronic diseases.
Finally, for those curious about their UPF intake, a practical suggestion would be to utilize nutrition fact labels. This can help in moderating consumption of UPFS and managing high sugars, saturated fats, and sodium, which aligns with well-established dietary research.





