Surging Respiratory Virus Raises Concerns as Flu Season Ends
Although flu season may be tapering off, it’s not time to pack away the tissues just yet.
A lesser-known respiratory virus, lacking both a vaccine and treatment, has been gaining traction since winter began, contributing to a rise in illnesses nationwide.
Wastewater analysis, which monitors pathogens in sewage to gauge community spread, indicates that these virus levels reached “high” status across the country by early March.
Interestingly, many experts believe that most Americans are oblivious to this virus, which produces symptoms resembling other respiratory issues like the common cold, flu, or RSV.
“People aren’t very familiar with it,” Dr. Sharon Nachman, who heads pediatric infectious diseases at Stony Brook Children’s Hospital, remarked. “When I hear someone say, ‘Oh my god, it’s March or April and I have the flu,’ my response is usually that, while you may look and feel like it, you likely have human metapneumovirus (HMPV).”
So, what exactly is this virus making people cough and sneeze as spring approaches?
Understanding HMPV
HMPV was first identified by researchers in the Netherlands in 2001, although evidence suggests it has been circulating among humans for at least fifty years prior to that.
This virus is seasonal, typically peaking in March or April before declining alongside warmer weather in May. “Now is just the right time for us to see it,” Nachman explained. “As flu season dwindles, this respiratory virus will take its place.”
Recognizing HMPV Symptoms
Most HMPV cases are mild and usually resolve within two to five days, with common symptoms like cough, fever, runny nose, sore throat, and wheezing. Occasionally, individuals may also develop a rash.
However, in some instances, the illness can escalate to pneumonia, bronchitis, or middle ear infections, and may exacerbate asthma or chronic lung conditions like COPD.
Typically, severe cases occur during a person’s first HMPV infection, which makes young children particularly susceptible. Older adults and those with compromised immune systems also face increased risks.
How Prevalent is HMPV?
Studies suggest that nearly everyone will contract some strain of HMPV at least once in their lifetime, with most infections occurring prior to age five. Among children, this virus accounts for nearly 12% of respiratory infections.
Despite its commonality, tracking HMPV remains a challenge. “It’s often not tested for when patients present with severe cold symptoms, which makes wastewater monitoring one of the few reliable methods to track its spread,” noted Dr. Alexandria Boehm, a professor at Stanford University.
When infected, individuals release HMPV markers through saliva, mucus, urine, and feces. “We can easily pick these up in wastewater in areas experiencing outbreaks,” Boehm elaborated.
Recent data from WastewaterSCAN indicates a 70% rise in viral activity since early February, with current levels of HMPV mirroring data from the same time last year.
Transmission of HMPV
HMPV spreads through direct contact with infected individuals or via touching surfaces contaminated by the virus. It is most contagious during the first few days of illness, remaining so for about one to two weeks. Symptoms generally appear three to seven days after exposure.
Diagnosis and Treatment of HMPV
Healthcare providers typically identify HMPV based on symptoms, but a nasal or throat swab can provide confirmation in a lab setting.
Currently, there is no vaccine and no specific treatment available for HMPV infections. Dr. Nachman pointed out that this might contribute to the general lack of knowledge about the virus. “There’s not really an urgency to diagnose it, as all I would say is that you have a viral illness—go home, rest, and have some chicken soup,” she quipped.
“These general remedies work for all viruses,” she added, emphasizing that staying hydrated and taking care of oneself is paramount for recovery. To minimize HMPV spread, the CDC advises staying home when feeling unwell, maintaining hand hygiene, and disinfecting frequently touched surfaces.





