Customized mRNA vaccines stimulate lasting T cell immunity in adjuvant TNBC

The main goal of this open-label, first-in-human, phase 1 umbrella trial (ClinicalTrials.gov: NCT02316457) was to evaluate the feasibility, safety, and tolerability of two types of mRNA–LPX-based vaccines: a standard warehouse vaccine made from non-mutated tumor-associated antigens (TAAs) and a custom-made, individualized neoantigen vaccine. The study particularly reports on the outcomes of the individualized neoantigen vaccine […]
Missing gut microbe in western infants sparks health concerns

Missing Microbe in Babies Raises Health Concerns Researchers have pinpointed a “missing microbe” frequently absent in infants from Western nations, suggesting that lifestyle changes might be impacting the crucial gut bacteria necessary for health. The decline of B. infantis emerged from a new global atlas of gut microbes. This study is part of a larger […]
My teenage son started a harmful habit to impress his friends. He was taken to the hospital with a serious lung issue… now I am making a desperate appeal.

Urgent Warning from Kentucky Mom After Son’s Lung Collapses Due to Vaping A mother from Kentucky is sounding the alarm following her son’s dual battles with collapsed lungs, which she believes stemmed from vaping. Seventeen-year-old Cameron Vann, known as Dodge, picked up vaping two years ago, initially to fit in with his peers at school, […]
Research Connects Meat Consumption to Reaching Age 100 — but the Nuances Matter

Study Suggests Meatless Diets May Impact Longevity in Older Adults A recent study involving thousands of Chinese adults indicates that those who avoid meat might be less likely to celebrate their 100th birthday compared to their meat-eating peers. However, it’s not as straightforward as it seems—it’s not simply a matter of “Eat meat, live longer.” […]
What I Learned About Style and Self-Value from Ozempic

Reflections on Weight Loss Journeys Last summer, during various work trips to places like Portland and New York, as well as my fall visits to London and Paris, I made an effort to reconnect with old friends, colleagues, and college classmates. I hoped someone would finally ask me that long-awaited question: Had I lost weight? […]
Cardiologists Hope You’ll Make These 5 Practices a Regular Habit

Key Points Cardiologists recommend small adjustments in daily habits to enhance heart health. Suggestions include increasing plant-based foods, staying active, socializing, and choosing unsweetened beverages. For smokers, seeking assistance to quit or at least reduce smoking is advisable. Heart disease remains the leading cause of death in the U.S., but there’s some uplifting news: according […]
The vaccine sector is not the adversary

Moderna’s Journey into Vaccine Development and Recent Challenges On December 30, 2020, I found myself boarding the first of two flights to Boston, feeling a mix of anxiety and determination, all while double-masked. My destination? Moderna’s manufacturing site, which sits just outside the city, where I was set to receive my first vaccine dose. Strangely […]
Highland High warns of more than a week of measles exposure as Utah hits 300 cases

Potential Measles Exposure at Highland High School SALT LAKE CITY — Students at Highland High School may have been exposed to measles for more than a week, as an infected student continued to attend classes. The Salt Lake County Health Department reported that the student was at school while infectious on February 6 and throughout […]
This mental exercise could reduce the risk of dementia for many years.

A little bit of brain training today could potentially help reduce the risk of Alzheimer’s disease and other forms of dementia for, well, at least 20 years. That’s what a recent study found, focusing on older adults who took part in cognitive exercises back in the 1990s aimed at boosting brain processing speed. The federally […]
Long Covid is still present. I understand – my life halted because of it.

Living with Long Covid: A Personal Journey I find myself 30 feet beneath the surface of the Blue Grotto, a stunning diving spot in central Florida. Here, embraced by the water and snug in my wetsuit, my blood pressure starts to even out. The long, deep breaths I take from my respirator keep my heart […]