Colorectal cancer has officially been identified as the leading cause of cancer-related deaths among individuals under 50, marking a notable shift from the fifth position it held in the 1990s. This conclusion comes from a recent analysis by the American Cancer Society, detailed in a study published in JAMA.
Researchers reviewed decades of national mortality statistics and found that colorectal cancer has overtaken other types of cancer—like lung, breast, brain cancers, and leukemia—in mortality rates for this age group. Overall, cancer deaths in those under 50 have decreased by around 44% since 1990, but colorectal cancer stands out as the only major cancer with significantly rising mortality rates among young people during this time.
Dr. Aparna Parikh, who leads the Young Adult Colorectal Cancer Center at Massachusetts Comprehensive Cancer Center, remarked that understanding the rising rates in young populations is an ongoing challenge. She suggested that various factors—including lifestyle and environmental exposures—might interact to increase an individual’s risk.
Key risk factors include family history, obesity, smoking, high alcohol consumption, a diet rich in red and processed meats, inflammatory bowel disease, and personal or family histories of polyps. To improve early detection, healthcare professionals stress the necessity of raising public awareness about symptoms associated with colorectal cancer.
Some early warning signs may include shifts in bowel habits, abdominal discomfort, rectal bleeding, fatigue, and unintentional weight loss.
The U.S. Preventive Services Task Force recommends that average-risk adults begin screening for colorectal cancer at age 45, continuing until age 75. Those with a family or genetic predisposition might need to start screenings even sooner. Individuals aged 75 to 85 should base their screening decisions on personal health status and preferences.
Dr. Parikh emphasized that while colonoscopy is often seen as the preferred screening method, alternate stool-based tests are also effective. It’s crucial that anyone experiencing symptoms such as weight loss, blood in the stool, or altered bowel habits seek a colonoscopy promptly.





