Researchers at the University of British Columbia (UBC) have developed what is believed to be a “groundbreaking coating.” Making medical devices safer.
For millions of patients, this could mean reducing the risk of thrombosis (or blood clot formation) and dangerous bleeding, according to a UBC press release.
The new material is designed for tubing in a variety of medical devices and mimics the “natural behavior of blood vessels.”
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This makes it safer to use blood contact deviceCatheters, stents, blood oxygenators, dialysis machines, and more, the release states.
Researchers have discovered a difference between bare and coated catheters. (Kizakkedatu Research Group)
This coating may be especially helpful when blood clots are a bigger concern.
anticoagulant The university says it is usually prescribed in high doses to prevent blood clots in machine users, but this can increase the risk of dangerous bleeding.
“This is a huge challenge because almost all synthetic materials activate blood upon contact.”
“By designing coatings that mimic the body's natural approach to preventing blood clots, we could dramatically reduce the need for dangerous blood thinners before and after patients use these devices. We have created a solution,” the study authors wrote in an email.
Dr. Jayachandran Kizackedatu, a professor of pathology and laboratory medicine at the University of British Columbia, told Fox News Digital that the discovery “could be a transformative step in the development of medicine.” Safer medical devices. ”
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The study, published in the journal Nature Materials, found that mimicking the body's own mechanisms, rather than repelling blood components, is “the key to designing truly biocompatible devices.” Confirmed, Kizakkedatu said.
Researchers say the new coating is designed to mimic the function of blood vessels, acting as a “soft barrier” that attracts important blood proteins and prevents them from clotting. (St. Petersburg)
Mr Kizhakkedathu said there had been a “steady increase” in the use of blood-contact devices over the past few decades, but this was “limited by the risk of blood clotting, and the risk of blood clots being detrimental to blood”. “There is a possibility that it will give.'' patient health. ”
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“This is a huge challenge because almost all synthetic materials activate blood upon contact,” he continued.
Kizhakkedathu says the long-term goal is to develop materials that can “essentially avoid coagulation activation.”
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“There is no effective way to prevent device thrombosis and inflammation, and despite extensive efforts, little progress has been made for decades,” he continued.
“There are increasing hopes for the development of highly improved medical devices that eliminate concerns about thrombosis,” the researchers said. (St. Petersburg)
“However, with our chemical design, we were able to develop a non-toxic polycationic molecule and a surface that prevents blood clotting.”
Kizhakkedathu said the development is still in its early stages and there is a need. Further research In more difficult cases and other animal models.
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“We hope this approach will inspire and benefit other scientists in this field,” he told FOX News Digital.
“There is growing hope for the development of highly improved medical devices that eliminate the concerns of thrombosis for the general public.”
