The upcoming week three of the 2025 NFL season brings an exciting matchup between the Miami Dolphins and the Buffalo Bills. Buffalo is favored heavily at home, with an 11.5-point lead and an over/under set at 49.5. The Bills are looking to secure a 3-0 record, while the Dolphins hope to avoid a disappointing start at 0-3.
Let’s delve into some of the best DFS plays for this Thursday night game.
James Cook, RB, Bills (flex $11,600, CPT $17,400)
Cook has continued his strong performance from last season and is currently among the top rushers in the league as week three approaches. His last game saw him accumulate 132 yards on 21 carries and two touchdowns in a 30-10 win against the Jets, earning 20 fantasy points for those managing DFS teams. With the short week, I think the Bills will rely heavily on their stars again, making Cook a solid pick for your lineup.
Tyreek Hill, WR, Dolphins (Flex $11,000, CPT $16,500)
After a frustrating first week, Hill rebounded with six receptions for 109 yards in a close 33-27 loss to the Patriots. Despite Miami’s rocky start to the season, he’s still Tua Tagovailoa’s primary target and has the potential to deliver strong performances. I anticipate they’ll work to get the ball into his hands as often as possible.
Bills Defense (flex $7,400, CPT $11,100)
The Bills’ defense has been impressive in the opening weeks, and this Thursday matchup seems favorable for them. Miami’s quarterback, Tua Tagovailoa, has been under pressure, ranking near the bottom for average time in the pocket. With injuries affecting Miami’s offensive line, there could be opportunities for Buffalo’s defense to capitalize with sacks and turnovers.
Matt Prater, K, Bills (flex $7,000, CPT $10,500)
Prater has been very reliable since joining the team, hitting all six of his field goal attempts and converting all five extra points. Given the offensive effectiveness and chance for defensive turnovers, he might have several scoring opportunities in this game.
Joshua Palmer, WR, Bills (Flex $5,400, CPT $8,100)
Palmer has been a dependable pass catcher for Buffalo, gathering 108 yards on seven catches from 12 targets over the first two games. While he hasn’t yet had a breakout performance in fantasy, he’s an affordable option who could provide a nice boost if he finds the end zone.
Nick Westbrook-Khine, WR, Dolphins (Flex $4,600, CPT $6,900)
Westbrook-Khine had three receptions for 25 yards, seeing limited action over two games. With Jaylen Waddle nursing a shoulder injury, he might play a more significant role if Waddle isn’t at full capacity. Taking a chance on Westbrook-Khine could be worthwhile in this matchup.
