The first week of the 2025 NFL season is underway, featuring the Grasshoppermore Ravens facing off against the Buffalo Bills in a rematch from last year’s AFC Division Round. Baltimore enters as the slight favorite, with a 1.5 point spread and an over/under set at 50.5. The Bills eliminated the Ravens from the playoffs last season, and this matchup could hint at a possible playoff encounter come January as both teams seek to establish dominance in the AFC.
Let’s explore some of the key DFS options for this evening’s game.
Zay Flowers, WR, Ravens (Flex $10,000, CPT $15,000)
Flowers missed last season’s divisional round against the Bills due to a knee injury and is eager to take on the challenge now. In 2024, he emerged as Lamar Jackson’s top target, recording 74 catches for four touchdowns and totaling 1,059 yards. With a target share of 25.4%, he ranked 20th in the league and has solid value as a captain choice.
Khalil Shakir, WR, Bills (Flex $9,400, CPT $14,100)
Shakir was Josh Allen’s primary option last season, leading the team with 100 targets and notching 76 receptions for 821 yards and four touchdowns. His 5.1 catches per game placed him 16th in the league, and he excelled in various statistical metrics. Like Flowers, he’s a strong candidate for the Captain slot, which could help build a well-rounded lineup.
Mark Andrews, TE, Ravens (Flex $8,600, CPT $12,900)
Andrews is looking to bounce back after dealing with drops in the previous season. He’s a crucial asset for Lamar Jackson and was a top red-zone tight end last year. Whenever the Ravens enter the red zone, he could find multiple scoring chances.
Deandre Hopkins, WR, Ravens (Flex $5,000, CPT $7,500)
Hopkins has joined the Ravens this season, adding another dimension to their offense. At 33, he may not be the same player he once was in Houston, but his current pricing is quite appealing as the season kicks off.
Ray Davis, RB, Bills (Flex $3,400, CPT $5,100)
Davis serves as the backup to James Cook and is likely to see some opportunities in this crucial opening game. Last season, he was notably effective in the red zone, scoring three touchdowns and recording 86 yards on 17 carries. He could be a handy addition to your roster.
Charlie Koller, TE, Ravens (Flex $1,200, CPT $1,800)
With Isaiah likely out due to an ankle injury, Koller will step in as the Ravens’ TE2 for the opener. The team utilized two tight ends frequently last year, and Koller showed solid efficiency during that time, suggesting he might earn some valuable targets.


