The NFL’s fourth week in 2025 kicks off with an NFC West rivalry game on Thursday night, where the Seattle Seahawks will square off against the Arizona Cardinals. The Seahawks enter as slight favorites, with a 1.5-point edge, and an over/under set at 43.5. Both teams are currently 2-1, and since every team in the division is above .500, losing this game could leave them lagging behind the pack.
Next, let’s dive into some top DFS picks for this Thursday night matchup.
Jaxon Smith-Njigba, WR, Seahawks (Flex $13,000, CPT $19,500)
Smith-Njigba has emerged as one of the standout wide receivers in the league this season. He boasts 22 receptions for 323 yards, contributing significantly to Seattle’s scoring efforts. Currently, he ranks among the top five in several categories, including receptions and receiving yards per route. With a remarkable target share of 40.28% on Seattle’s offense, he’s definitely making an impact. Averaging 17.9 fantasy points per Fanduel game, he’s the highest-priced player in this matchup, but given his performance, I believe he’s worth the investment.
Sam Darnold, QB, Cardinals (Flex $13,000, CPT $18,000)
Darnold has enjoyed solid protection this season, which contributed to his impressive outing last week—a 44-13 victory over the Saints. In that game, he completed 14 out of 18 passes for 218 yards and two touchdowns. With a low sack rate at 3.85%, he has also been effective in moving the ball, aided by playmakers like Coop P and Kenneth Walker, alongside Smith-Njigba. It might be a good idea to consider him for your lineup.
Trey Benson, RB, Cardinals (Flex $13,800, CPT $9,200)
With James Connor sidelined due to an ankle injury sustained against the 49ers, Benson is set to take on a starting role. The second-year running back from Florida has already made a strong impression, averaging 6.0 yards over 21 rushing attempts. He’s also contributed with eight receptions in just two games, making him a versatile option for Arizona’s offense. I think he has the potential to perform well as a starter, so he’s worth considering for your captain spot.
Tory Horton, WR, Seahawks (Flex $5,400, CPT $8,100)
Horton has shown his value in various roles for the Seahawks, particularly evident in the last game against the Saints, where he had a standout 95-yard punt return. His abilities on offense and special teams could be crucial for Seattle, making him a solid addition to your lineup.
Emari Demarcado, RB, Cardinals (Flex $4,200, CPT $6,300)
As Benson steps into the starter role, Demarcado will take on the position of RB2 for Arizona. Although he’s only had two carries this season, he has shown reliability over the past two years. He could be an interesting, budget-friendly option, especially if Arizona sticks to a straightforward running game in this prime-time matchup.
Elijah Higgins, TE, Cardinals (Flex $3,200, CPT $4,800)
Seattle has struggled against tight ends this season, allowing a league-high 50 fantasy points on Fanduel. Higgins has recorded just four receptions for 55 yards in three games, but considering the Seahawks’ vulnerability at this position, he might be worth a look as a low-cost option.
