New Jersey Man’s Death Linked to Tick-Borne Meat Allergy
For the first time, researchers at UVA Health in Virginia have associated a New Jersey man’s death with a tick-borne meat allergy. The man, aged 47 and not publicly named, reportedly died just four hours after consuming a hamburger last summer. Interestingly, this incident followed a similar episode where a steak had caused him severe symptoms only two weeks earlier.
A press release from UVA Health mentions a summer incident where the same man experienced intense abdominal pain, diarrhea, and vomiting after eating steak. Initially classified as a “sudden unexplained death,” it was later determined by Dr. Thomas Platts-Mills from UVA Health that the man may have experienced a life-threatening allergic reaction.
The findings were published in The Journal of Allergy and Clinical Immunology: In Practice. The allergy in question is known as alpha-gal syndrome (AGS), often referred to as the “red meat allergy” or “tick bite meat allergy.” It’s caused by bites from the Lone Star tick, predominantly found in certain southeastern and eastern states, according to the Centers for Disease Control and Prevention.
The tick’s saliva introduces a sugar molecule called alpha-gal into the body, which can provoke allergies to various types of red meat, including pork, beef, rabbit, lamb, or even products derived from mammals like cheese and milk.
Researchers note that reactions can range from severe allergic symptoms occurring a few hours after ingesting an allergen to mild cases. Symptoms may include rashes, nausea, vomiting, and even swelling of the lips, face, or throat. Some individuals also report wheezing and difficulty breathing, as outlined by the Mayo Clinic.
While fatal anaphylaxis is a rare risk, this incident marks the first reported death in New Jersey tied to the allergy. Dr. Platts-Mills speculated that other factors might have played a role in the man’s severe reaction, such as the beer he consumed alongside the burger, exposure to ragweed pollen, and recent physical activity.
“It’s crucial for the public to understand that severe abdominal pain that arises three to five hours after eating certain meats should be taken seriously and examined for potential anaphylaxis,” Platts-Mills stated. He also mentioned that individuals who experience persistent itching for more than a week should be evaluated for similar allergies. Furthermore, he noted that tick bites can enhance sensitivity to mammalian meat.
In general, individuals with mild to moderate symptoms can often manage their condition through dietary adjustments. Diagnosis of AGS typically necessitates antibody tests, and many patients encounter a lengthy path to diagnosis, averaging around seven years, as Dr. Johanna Salzer from the CDC pointed out.
After receiving a diagnosis, some patients may have to deal with AGS for life, though some find that abstaining from particular foods can lead to a decrease in antibody levels over time. Presently, there’s no known cure for AGS, but healthcare providers can assist patients in managing their symptoms effectively.
Experts advise that those experiencing severe reactions should be equipped with an EpiPen in case of anaphylactic shock.
Prevention Tips
To mitigate the risk of tick bites, Dr. Sulzer recommends using EPA-approved insect repellents, especially those that contain active ingredients like DEET or oil of lemon eucalyptus. Wearing long sleeves, long pants, and socks and steering clear of dense grassy or wooded areas can be beneficial as well.
After spending time in areas where ticks thrive, it’s wise to shower and conduct a thorough body check. Dr. Platts-Mills encourages individuals in regions with prevalent Lone Star ticks to be vigilant about the potential risks associated with them. Particularly, unexpected severe abdominal pain after consuming mammalian meat should prompt an investigation into possible sensitization to alpha-gal.


