Pain from knee arthritis is commonly addressed with medication, injections, or medical devices. However, recent research indicates that simpler physical therapies might provide more significant relief with fewer risks for many individuals.
A new study involving thousands of patients highlights knee braces, warm water therapy, and structured exercise as effective solutions for managing knee arthritis pain. These methods allow people to walk and climb stairs more comfortably without introducing new medications.
Osteoarthritis and Pills
Many individuals diagnosed with osteoarthritis, a degenerative joint condition that gradually damages cartilage and restricts movement, are typically advised to control their pain using medication. Currently, around 528 million people worldwide live with osteoarthritis, with approximately 365 million experiencing knee-related issues.
The research was led by Yuan Luo, a rehabilitation expert at Neijiang’s First People’s Hospital in southwest China. Luo aims to assess various non-drug therapies for knee osteoarthritis, helping patients steer clear of unnecessary medication side effects.
For many, nonsteroidal anti-inflammatory drugs (NSAIDs) are a common solution for knee arthritis pain, though these medications can adversely affect the stomach. Concerns also arise regarding the long-term impact of these drugs on kidney function and heart health, especially among older adults.
A comprehensive review concerning NSAID usage in individuals over 60 reported increased incidences of serious gastrointestinal bleeding and kidney damage among regular users. The study also linked prolonged NSAID use to higher rates of cardiovascular events.
What This Study Did Differently
Unlike studies that typically evaluate a single treatment, Luo’s team compared a variety of therapies simultaneously. They employed a network meta-analysis—a method that aggregates results from different trials—allowing for a cohesive ranking of treatment effectiveness.
To develop this comparison, researchers combined data from 139 trials that evaluated 12 non-drug options for knee osteoarthritis. These trials included assessments of laser therapy, electrical stimulation, braces, insoles, taping, ultrasound, hydrotherapy, and several exercise programs.
They rated pain, stiffness, and day-to-day functionality using standard assessment scales, which helped provide a clearer overall picture without letting any single small study skew the results.
“Our analysis of nearly 10,000 patients shows that straightforward therapies like knee bracing and water-based exercise surpass high-tech options like ultrasound. This could change clinical guidelines to emphasize safer, more affordable interventions,” said Luo.
How Braces Shift the Load
A knee brace designed for arthritis typically consists of a rigid or semi-rigid structure that encircles the joint. By redistributing body weight across the knee, the brace alleviates pressure from the worn area and minimizes irritation of sensitive tissues.
Clinical studies focusing on unloader braces—rigid supports that relieve pressure from one side of the knee—demonstrate significant short-term pain reduction. Many trials also report improved functionality and increased walking distances for users of these braces.
An overview of 14 studies on braces indicated that many individuals experienced a better overall quality of life while using them. There are also early indications that bracing may postpone the need for knee replacement surgery for some patients.
However, there are some downsides, such as bulkiness, skin irritation, and the inconvenience of wearing them for long periods. Real-world studies suggest that many users either stop using their brace or wear it only intermittently, meaning comfort and fit play crucial roles in their effectiveness.
Why Water and Exercise Matter
Hydrotherapy involves guided exercises performed in warm water that reduce joint impact while supporting body weight, allowing for a more comfortable range of motion.
A systematic analysis of aquatic exercise programs found that water-based sessions significantly alleviate pain and joint dysfunction for those with osteoarthritis, especially for participants who find land exercises challenging due to pain or balance issues. In Luo’s comprehensive ranking, hydrotherapy emerged as a leading option when evaluating combined arthritis scores, addressing pain, stiffness, and daily functionality together.
This trend aligns with feedback from programs tailored for older adults with knee arthritis. In warm water, participants can work on balance, strength, and walking practices without the jolting discomfort associated with ground workouts.
Land-based exercise remains a key component of care for individuals with knee osteoarthritis. Recommendations include walking, strengthening exercises, simple balance drills, supervised sessions, and adequate support for weight management and self-care.
What This Means for Treatment
This new ranking advocates for a treatment model where braces, exercise, and hydrotherapy form the foundation of long-term care. In this framework, medications are cautiously used as secondary options rather than the default first step.
Since these physical therapies address the root causes of pain—by redistributing load, strengthening muscles, and retraining movement patterns—they often hold more significance than brief medication courses.
International guidelines now recommend tailoring combinations of non-drug and drug therapies to better meet the unique needs of each person experiencing knee symptoms.
Bracing and structured exercise are among the most strongly supported approaches for alleviating painful knee osteoarthritis, frequently integrating bracing for high-demand activities with routine supervised exercise sessions.
When available, incorporating aquatic therapy and short-term medications during flare-ups are preferred over immediately resorting to injections or surgery.
More to Learn About Osteoarthritis
Individuals with knee arthritis should consult their healthcare provider about the appropriateness of unloading braces or supervised exercise programs based on their specific circumstances.
It may also be beneficial to inquire about aquatic therapy if issues like balance or weight make land exercises difficult.
Discussions about brace fitting, hours of wear, and suitable exercises can help customize treatment, potentially enhancing comfort and adherence. Specific goals—like hiking, kneeling, or climbing stairs—can direct focus to the therapies that warrant the most attention.
Further research is necessary to conduct longer studies tracking brace users and exercise participants over several years. Such trials will help determine if these methods effectively delay the need for joint replacements and remain cost-efficient as individuals age.
Luo and his team also point out that combining therapies, such as bracing alongside hydrotherapy, might deliver even greater benefits than any single treatment option. However, comprehensive trials to evaluate those combinations are still scarce, so understanding the optimal mix and timing of therapies remains an open question.
The study is available in PLOS One.





