Novo Nordisk Reduces Prices for Ozempic and Wigovy

Dr. Mahasa Tehrani, a board-certified rheumatologist, recently discussed Novo Nordisk’s choice to lower the U.S. list prices for the widely used diabetes and weight-loss medications, Ozempic and Wigovy, during an interview with America Report.

People using GLP-1 (glucagon-like peptide-1) drugs for managing diabetes or shedding pounds often mention experiencing gastrointestinal issues. Interestingly, there are also some lesser-known side effects that have emerged, one of which is informally called “Ozempic breath.” Dr. Neha Lalani, an endocrinologist from Lakeway, Texas, explained that this term refers to a “fishy smell” that can occur in burps and bad breath.

Though bad breath, known medically as halitosis, isn’t officially listed as a side effect of semaglutide (Ozempic, Wegovy) and tirzepatide (Monjouro, Zepbound), it does seem to be influencing consumer behavior. For example, during a recent earnings call, the CEO of Hershey’s noted that the rise in GLP-1 drug usage has prompted an increase in gum and mint purchases among consumers looking to freshen their breath.

At this point, no peer-reviewed research has confirmed that these medications cause bad breath, nor have the mechanisms behind this phenomenon been fully explained. Nevertheless, many users have taken to social media to share their experiences with “Ozempic breath.”

One user expressed frustration, saying, “Even when I brush my teeth and use mouthwash, I still smell it—like a dirty drain or sewage.” Another user mentioned feeling the need to frequently brush their teeth, noting, “The sulfur burps were annoying, albeit temporary.”

Dr. Sue Decotis, an internist from New York City who focuses on medical weight loss and hormone optimization, highlighted that bad breath can stem from a variety of factors such as dehydration, gastric reflux, medication side effects, and an unhealthy gut microbiome. She emphasized the importance of staying hydrated, stating that even moderate doses of GLP-1 drugs necessitate substantial water intake—around a gallon daily—to support fat metabolism and effective hydration.

Dr. Decotis suggested that using a balanced probiotic may be beneficial, especially for those who experience reflux. Ensuring adequate protein and fiber consumption can also promote gastrointestinal health.

In an effort to combat the breath issue, some users have shared their personal tips. One individual noted on Reddit that maintaining hydration helps improve taste and odor. Another advised cutting out fatty and processed foods, which they found helpful. Some users have also reported that antacids and fiber supplements might offer some relief.

If someone experiences persistent bad breath or unusual gastrointestinal symptoms while taking GLP-1 medications, it’s strongly recommended that they consult their healthcare provider for further evaluation and guidance.

Novo Nordisk has been contacted for further comments on this matter.