In recent times, Ozempic has become a popular choice for those looking to lose weight.
However, some health professionals and numerous social media users are speculating that we might be entering a new phase, referred to as the “Vozenpick” era.
“Fake Sempic” or “False Ozempic” mainly refers to products that are falsely marketed as mimicking the effects of GLP-1. Yet, it also includes a surge of GLP-1 enhancers and natural alternatives that claim benefits ranging from better fat burning to enhanced gut health, improved digestion, and, of course, weight reduction.
According to a report by Grand View Research, the global market for weight loss supplements was valued at approximately $33.14 billion in 2024 and is anticipated to increase to about $71.59 billion by 2030, growing at an annual rate of around 14.17% from 2025 to 2030.
Caitlin Bedford, a nutritionist and founder of Wellness the Right Way, which specializes in weight management, points out that there has been a notable rise in the marketing of supplements as ‘natural GLP-1 activators’ or their substitutes.
Various trending brands like Lemme, HUM Nutrition, Love Wellness, and Sakara Life have launched their own metabolic boosters and GLP-1 support products.
Bedford admits that while many key ingredients are scientifically backed, they don’t function in the same way as GLP-1 medications.
“These products often incorporate ingredients like fiber, berberine, and green tea extract. While they may provide some metabolic benefits, they lack the effectiveness of GLP-1 medications,” she noted.
As someone who focuses on weight loss counseling, Bedford said she’s noticing rising interest in these products. However, she warns that many GLP-1 activators are “frequently underregulated and often overhyped,” which can lead to misleading claims.
She elaborates, “Supplements aren’t regulated to the same extent as medications, so their quality, dosage, and safety can vary immensely. People should be cautious of proprietary blends and exaggerated marketing claims, especially those promising quick fixes for weight loss.”
If someone is interested in trying a GLP-1 activator, Bedford advises carefully checking for clinical research backing the formulation and selecting a reputable brand that has undergone third-party testing. Ultimately, she still promotes adopting sustainable, evidence-based approaches over reliance on supplements.
“Nutritionally, it’s essential to focus on protein intake—typically around 1.2 to 1.6 grams per kilogram of body weight—to support fullness and preserve lean body mass. Additionally, adequate fiber intake helps manage appetite and blood sugar levels,” she recommends.
She urges combining a balanced diet with consistent exercise, suggesting incorporating simple at-home workout equipment and fitness tracking to motivate clients.
Below are Bedford’s recommendations for practical tools that can aid weight loss.
Supplement Recommendations for Weight Loss by Bedford
Overall Grand Prize: Thorne Berberine HCI and Phytosome Supplement
When considering weight loss support supplements, Bedford advises looking for a straightforward berberine option from a trustworthy source.
A meta-analysis has shown noteworthy decreases in body weight, BMI, and waist size linked to berberine consumption, potentially aiding metabolic health.
“Thorne conducts extensive third-party testing and is friendly for those with allergies,” Bedford shared. Their formula combines two berberine extracts: 450 milligrams of berberine hydrochloride and 550 milligrams of berberine phytosomes, believed to boost absorption.”
Best for Feeling Full: Truvani Protein Powder
Bedford also encourages clients to choose clean protein powders.
Research indicates that a high-protein diet is a safe and effective method for weight loss while helping to prevent obesity and related diseases.
She notes that it’s vital to opt for a protein powder free of unnecessary additives but still palatable enough for daily use. Truvani is one she particularly recommends.
“Our ingredients are of high quality with no unnecessary fillers, aligning nicely with a holistic nutrition approach,” Bedford explained. “It’s a convenient way for busy clients to meet their protein requirements for fullness, muscle maintenance, and weight management.”
Great for Digestion: Garden of Life Prebiotic Fiber
Dr. Bedford underscores nourishing a healthy gut microbiome as crucial for regulating hunger hormones and aiding digestion—both of which are significant in managing weight. Prebiotic fiber acts as nutrition for beneficial gut bacteria, fostering a balanced ecosystem.
A 2020 study concluded that prebiotic fiber has the ability to favorably modify the gut microbiome and shows promise as a dietary strategy.
Bedford recommends the Garden of Life blend, which contains 5 grams of fiber per serving sourced from nutrient-rich superfoods like cassia, orange and apple peel, and cranberry fruit.
“This prebiotic fiber supplement supports gut health, which is vital for weight regulation and overall wellness. I often suggest fiber supplements to clients struggling to reach their daily intake from whole foods, as they can also enhance satiety and help keep blood sugar stable,” she added.
More About Bedford’s Weight Loss Recommendations
Great for Meal Planning: Meal Prep Containers
“Structured meal prep is one of the most effective behavior changes for weight management,” Bedford argues, recommending meal prep containers for portioning meals.
A study found that frequent meal planning is associated with improved weight loss results in programs focused on behavior change. Participants planning meals tended to lose more weight than those primarily concentrating on exercise frequency.
“These containers aid clients in maintaining portion control, reducing dependence on takeout, and making healthy meals easier to access during hectic weeks,” she added.
Perfect for Exercise: Rose Bangle Wrist & Ankle Weights
For weight management goals, the Mayo Clinic advises engaging in a minimum of 150 minutes of moderate aerobic activity weekly, or around 75 minutes of vigorous exercise.
Bedford emphasizes that exercise should play a vital role as well. Fortunately, many budget-friendly home workout tools can ramp up intensity and elevate heart rates without the expense of fitness classes or gym fees. She particularly likes rose bangles.
“These subtly boost daily energy expenditure without necessitating a formal training session,” Bedford remarked. “I find them effective for clients who seek consistent movement because they enhance everyday activities in a friendly, non-intimidating way.”
Great for Tracking Your Health: Fitbit Charge 6 Fitness Tracker with Google Apps
Numerous weight loss specialists are now utilizing fitness trackers to assist patients in monitoring goals and progress, even if data on newer devices is still somewhat sparse.
A systematic review suggests while there’s some evidence indicating wearable devices can promote increased long-term physical activity and support weight loss, it has not shown a definitive advantage over traditional methods.
Regardless, Bedford believes Fitbit is a useful gadget that gathers a wealth of information, from steps taken to stress and sleep levels, also providing advanced coaching tips.
“It’s a splendid tool for tracking activities and staying aligned with weight loss goals,” Bedford emphasizes. “It helps monitor progress efficiently.”
Weight Loss FAQ
Which Diet or Weight Loss Trends Should Patients Avoid?
Bedford firmly advises against extreme or unsustainable diets.
“This includes very low-calorie diets meant to mimic GLP-1 effects through serious calorie restrictions, which can prompt muscle loss and nutrient deficiencies,” she warns.
She also notes that detoxes and cleanses, while trendy, lack scientific backing and can disrupt protein intake and blood sugar stability.
What Should Clients Consider Before Starting GLP-1?
Before beginning GLP-1 treatment, Bedford stresses that it is just a tool, not a substitute for meaningful lifestyle changes.
“To achieve lasting results, patients should commit to developing sustainable nutrition and exercise habits along with medication,” she mentioned. “I also advise maintaining protein intake, hydration, and micronutrient levels, as appetite suppression can lead to reduced overall intake.”
She also highlights the necessity of screening, especially for individuals with a history of eating disorders, gastrointestinal issues, gallbladder disease, or specific thyroid cancers.
What Are Some Common Side Effects Related to GLP-1?
“The most commonly observed side effects include nausea, constipation, early fullness, and fatigue. A significant concern nutrition-wise is unintentional muscle loss if protein intake and strength training aren’t emphasized,” noted Bedford.
What Qualifications Should Be Considered in Commercially Available Supplements for Weight Loss?
From her clinical view, Bedford advocates for supplements that have completed third-party testing (like NSF Sports Certification or USP Verification).
She also urges consulting a doctor before starting any new supplements to ensure they won’t interfere with existing medications.
“Above all, supplements should complement rather than substitute for good nutrition and lifestyle strategies,” she stressed.
What Diet and Exercise Tips for People Trying to Lose Weight Without Taking GLP-1?
For those not using GLP-1 drugs, Bedford focuses on sustainable, evidence-informed strategies, promoting protein intake and fiber consumption.
“Rather than resorting to drastic restrictions, we recommend a moderate calorie deficit paired with plenty of nutrient-rich foods like fruits, vegetables, and lean proteins,” she suggests. “Consistency is crucial behaviorally. A structured diet, sufficient sleep, and stress management are key components.”
Regarding exercise, she emphasizes strength training’s importance to “maintain muscle mass and enhance metabolic health during weight loss.” She also encourages daily movement and incorporating cardio as a supporting activity rather than the main focus.
