A fundamental review of transgender treatment for minors has discovered “deep uncertainty about the benefits” of many of these interventions. He also urged doctors to focus on behavioral therapy when dealing with gender discomfort.
The researchers also concluded that many of the protocols for treating children with gender dysphoria are widely used before deciding whether outcome studies are safe practices, according to a 409-page health and welfare welfare study.
“The umbrella review found that the overall quality of evidence regarding psychological outcomes, quality of life, regret, or the effects of interventions on long-term health is very low.” HHS Gender Discomfort Report has been decided In the evaluation of general research on transgender treatment.
“This indicates that the beneficial effects reported in the literature are likely to differ significantly from the true effects of the intervention.”
President Trump signed Presidential Order In January, he ordered HHS to conduct a review of best practices to treat gender dysphoria within the 90 days released on Thursday.
Children's transgender interventions vetted in the hit HHS report include the use of adolescent blockers, hormone therapy, and surgical treatment.
The report emphasized that it is not a “clinical practice guidelines,” but the paper examined 17 systematic reviews of transgender treatment in minors and concluded that there is limited evidence to suggest that these interventions have “meaning improvements in mental health.”
In some cases, this was because the study did not properly measure individuals who tracked patient outcomes or studied mental health as being “highly functional at baseline.”
“Multiple SRs [systematic reviews] Evidence supporting the benefits of pediatric transition interventions from PBS is [puberty blockers] to csh [cross-sex hormone therapy] And surgery – “very low certainty,” the HHS report states.
“All medical interventions have potential harm.”
Much of the research on transgenderism in question has been conducted overseas. One of the most famous was the Dutch protocol. It was first published in 2006 and outlined “highly medicalized” methods for treating young people with gender discomfort, including adolescent blockers.
For many years, Dutch protocols have generally been viewed as gold standard guidelines for treating young people suffering from gender discomfort. The guidance has since weakened over time, with some of its eligibility restrictions being reduced.
Following the publication of Dutch protocols in 2006, transgender treatment for minors had risen sharply.
An estimated 3.3% of US adolescents consider themselves transgender, according to the HHS report. Meanwhile, about 0.1% of 17-year-olds received hormone treatment between 2018 and 2022.
However, researchers at HHS have discovered that the Dutch protocol is based on a “methodological flaw” that has been “largely overlooked” by the wider medical community since its publication.
“One limitation of the study was to retrospectively select 70 subjects from the 111 larger “intention to treatment” groups using non-randomised methods,” the HHS report states.
“This selection process inadvertently biases the sample to the most favorable prognostic cases, limiting the generalizability of the findings of the study.”
The HHS study warned that there was “extreme toxicity and polarization surrounding this field of medicine.”
Researchers in the HHS Report frequently pointed out UK Cass Reviews. This is a four-year, drastic study by the National Health Service that has similarly plunged into the metrological hall in a more general study on transgenderism.
They also acknowledged that there is “growth in international concerns about the pediatric care transition,” and that foreign countries are increasingly restricting the treatment of transgender minors.
“There is currently no international consensus on best practices for caring for children and adolescents with gender discomfort,” the HHS report emphasized.
Nevertheless, medical ethicists, physicians, and methodologies compiled the HHS review highlighted the potential benefits of psychotherapeutic approaches to addressing minor gender discomfort.
Researchers at HHS acknowledged that “direct evidence of psychotherapy” in children with gender violations is limited, but “argued that there is available evidence in support of the role of psychotherapy.
Treat children and adolescents with other mental health issues, such as depression.
The research on HHS is filled with mixed reactions from the medical community.
Susan Cresley, president of the American Academy of Pediatrics, denounced the report, claiming it relied heavily on a “small set of data” and “choosing perspective.”
“This report misrepresents the current healthcare consensus and does not reflect the reality of pediatric care.” ” She said in a statement.
Dr. Stanley Goldfarb, chairman of Do No Harm, an organization opposed to so-called gender transition surgery, welcomed the HHS review to expose “many serious risks in the medical transition of young people.”
“The report cites the 'lack of robust evidence' of these medical procedures,” Goldfarb said in a statement. “Now, it's now more clear than ever that this misguided practice must be completed and replaced with evidence-based treatment for a child with a confused gender.”
Trump's HHS research directive was surrounded by a broader January executive order to cut off government funding to support or promote operations for child sex change.
Dr. Jay Bhatacharya, Director of the National Institutes of Health (NIH), who supports the implementation of HHS research, stressed the need for political agenda to not interfere with science.
“Our duty is to protect the children of our country, not to expose them to unproven irreversible medical interventions,” Bhatacharya said. “We must follow the gold standard of science, not the activist agenda.”
Now released, the HHS study entitled “Treatment of Childhood Gender Discomfort: A Review of Evidence and Best Practices” will be peer-reviewed.
Once the peer review process is complete, you can expect a modified version of the report.

