Impact of Ultra-Processed Foods on Mental Health
We often turn to comfort foods like pizza or ice cream during tough times, but recent studies highlight some serious downsides to consuming ultra-processed foods (UPFs), such as donuts. These findings suggest that these foods might be more harmful than we realize.
This week, the Lancet medical journal revealed alarming research indicating that UPFs could be contributing to a “pandemic of chronic diseases.” It’s probably not surprising to many—after all, UPFs are often loaded with calories, sugar, fat, and salt, leading to obesity and associated health issues like heart disease, stroke, and type 2 diabetes.
Experts globally have raised concerns about diets high in UPFs being linked to kidney disease, inflammatory bowel disease, and even certain cancers. However, one significant aspect that hasn’t received enough attention is its connection to depression.
Research from Pakistan indicates that consuming large amounts of UPFs may increase the risk of developing depression by 20-50%. This condition involves a persistent sense of sadness and a lack of motivation. The study’s authors noted, “This association remains significant even after accounting for various factors,” as mentioned in the European Medical Journal Gastroenterology.
To reach their conclusions, researchers analyzed nine studies with over 79,700 participants, which certainly adds credibility to their findings.
Several theories explain this link between UPFs and depression. For instance, junk food can cause blood sugar spikes that often lead to negative moods and heightened stress levels. Moreover, UPFs tend to be deficient in essential nutrients such as B vitamins, vitamin D, magnesium, and omega-3 fatty acids—nutrients necessary for maintaining brain health.
The relationship between gut health and mental well-being is also essential. “Studies reveal that the gut microbiota in individuals suffering from depression differs significantly from that of healthy individuals,” the Pakistani researchers noted. They suggested that gut bacteria might interact with the nervous system, potentially leading to depressive symptoms.
The researchers emphasized that gut bacteria produce mood-affecting chemicals like serotonin and dopamine. When the balance of these bacteria is disrupted, it can alter neurotransmitter levels.
Of course, one solution would be to cut out UPFs completely. But realistically, that’s not so simple. UPFs are prevalent and account for about 55% of total calories in an average American diet.
Dr. Eva Serhab, a contributing editor at Harvard Health Publishing, offers practical advice. She suggests reflecting on how these foods impact your mood and overall well-being.
Her recommendation? Try a “clean” diet—so, no sugar or processed foods for two to three weeks. If it’s packaged, it’s best avoided. After this period, gradually reintroduce foods one at a time to monitor how you feel.





