Keto Diet Shows Potential in Alleviating Depression Symptoms
The ketogenic diet, often referred to as “keto,” has gained traction as a weight loss strategy for many. Recently, researchers from Ohio State University (OSU) found that a low-carb, high-fat diet can potentially help alleviate symptoms of depression.
A press release highlighted a notable 70% reduction in depression symptoms among 16 OSU students who adhered to a structured keto diet for at least 10 weeks. Interestingly, while previous studies indicate that medications and counseling can cut depressive symptoms by around 50%, the students in this study saw notable improvements, with a 37% decrease in their scores by just the second week.
Beyond just symptom relief, this research also observed remarkable increases in the students’ “global happiness,” along with enhancements in memory, executive function, and processing speed. Weight loss was another common outcome; nearly all participants shed an average of 11 pounds and experienced a modest reduction in body fat percentage.
The cohort comprised 10 women and six men, averaging 24 years old. Notably, many had previously received treatment for depression, whether through medication, counseling, or both.
The keto diet involved a significant reduction in carbohydrates—less than 50 grams per day—combined with higher fats and moderate protein intake. Participants were instructed to eat intuitively, focusing on fullness rather than calorie counting.
According to OSU’s researchers, the diet promotes the production of ketones, which serve as an alternative fuel source for the brain and body. This state of nutritional ketosis appears to assist in both mood regulation and cognitive functionality.
Lead author Dr. Jeff Volek remarked on the unexpected magnitude of improvement. He noted, “There’s substantial evidence that ketones can enhance brain function and influence mood through various neurochemicals.” Specifically, ketones may directly affect neurotransmitters linked to depression.
Volek further explained that, in addition to promoting mood improvements, ketones possess anti-inflammatory properties. He also connected weight loss to improved mental health, pointing out that there’s often a correlation between obesity and depression.
For those grappling with mental health challenges, there’s a suggestion to explore diverse dietary patterns. Volek indicated that the keto diet might be a valuable resource and encouraged individuals seeking help to understand its principles and find the necessary support.
Researcher Ryan Patel from OSU noted that stress, anxiety, and depression are major hurdles for students’ academic performance. He highlighted that approximately 40% of students report experiencing depression, with many not receiving adequate treatment.
Patel emphasized the need for solutions to support students on a larger scale, stressing the potential of nutrition as a key component.
Lastly, one limitation of the study was the lack of a keto-control group, which the researchers noted for future trials. This pilot study was backed by a grant from the Baszucki Group Brain Research Fund.
