COVID-19 Vaccine Reduces Heart Risks in Veterans
A recent study suggests that the 2024-2025 COVID-19 vaccine has been associated with a decrease in serious heart-related incidents among veterans in the U.S.
This research shows a slight drop in cardiovascular events linked to COVID-19, termed COVID-19-associated MACE (major adverse cardiovascular events). MACE generally includes severe outcomes like cardiovascular death, heart attacks, strokes, and hospitalizations due to heart failure.
Using health data from the U.S. Department of Veterans Affairs, researchers analyzed records of two groups of veterans. One group, almost 350,000 strong, received both the COVID and flu vaccines on the same day, while the other group, around 700,000, only received the flu vaccine.
Among the over one million veterans analyzed, the average age was approximately 70, with 92% being male. After about eight months, findings indicated that those vaccinated with the 2024-2025 COVID vaccine experienced a reduced risk of major cardiovascular events associated with COVID, showing a relative vaccine effectiveness of 37.7%.
The vaccine was linked to a 57.9% lower risk of death from cardiovascular issues, a 38.5% reduction in heart attacks, and a 41.9% decrease in hospitalizations for heart failure. However, the results concerning strokes were not statistically significant.
The vaccine’s effectiveness was particularly pronounced among older adults, especially those aged 75 and above, with a noted effectiveness rate of 50.7% in preventing COVID-related MACE in this age group.
It’s important to note that this study was observational, meaning it couldn’t definitively prove a causative link between the COVID-19 vaccine and the reduced risk of cardiovascular events. Rather, it underscored a correlation.
Dr. Glenn Hirsch, a cardiologist at National Jewish Health in Denver, remarked that these findings were “not overall surprising.” He pointed out that previous studies have shown vaccines can help prevent cardiovascular events related to infectious diseases.
Dr. Hirsch explained that infections such as COVID-19 can lead to acute inflammation, which heightens the risk of cardiovascular complications. This inflammation can promote blood clotting and make arterial plaques more susceptible to rupture, potentially resulting in serious heart events.
Although these outcomes are beneficial, Hirsch noted that the overall impact of the vaccine observed in this research was less significant than findings from earlier studies. Factors such as lower severity of illness from recent COVID-19 variants and increased immunity from infections in unvaccinated individuals could have influenced these results.
In summary, while the study indicates that the COVID-19 vaccination provides certain heart health benefits, it’s essential for individuals to consult with healthcare professionals about their vaccination options annually.
Additionally, Dr. Hirsch cautioned that the study’s observational nature means there could still be confounding factors after necessary adjustments, and some potential adverse effects of the vaccines were not explored.





